Introduction
In this vignette, CTX Bioactivity API will be explored.
NOTE: Please see the introductory vignette for an overview of the ccdR package and initial set up instruction with API key storage.
Data provided by the API’s Bioactivity endpoints are sourced from ToxCast’s invitrodb.
US EPA’s Toxicity Forecaster (ToxCast) program makes in vitro medium- and high-throughput screening assay data publicly available for prioritization and hazard characterization of thousands of chemicals.
The ToxCast pipeline (tcpl) is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, invitrodb . These assays comprise Tier 2-3 of the new Computational Toxicology Blueprint, and employ automated chemical screening technologies, to evaluate the effects of chemical exposure on living cells and biological macromolecules, such as proteins (Thomas et al., 2019). More information on the ToxCast program can be found at https://www.epa.gov/comptox-tools/toxicity-forecasting-toxcast.
This flexible analysis pipeline is capable of efficiently processing and storing large volumes of data. The diverse data, received in heterogeneous formats from numerous vendors, are transformed to a standard computable format and loaded into the invitrodb database by vendor-specific R scripts. Once data is loaded into the database, ToxCast utilizes generalized processing functions provided in this package to process, normalize, model, qualify, and visualize the data.
The Bioactivity API endpoints are organized into two different resources, “Assay” and “Data”. “Assay” resource endpoints provide assay metadata for specific or all invitrodb ‘aeids’ (assay endpoint ids). These include annotations from invitrodb’s assay, assay_component, assay_component_endpoint, assay_list, assay_source, and gene tables, all returned in a by-aeid format.
“Data” resource endpoints are split into summary data (by ‘aeid’) and bioactivity data by ‘m4id’ (i.e. both ‘aeid’ and ‘spid’). The summary endpoint returns the number of active hits and total multi- and single-concentration chemicals tested for specific ‘aeids’. The other endpoints return chemical information, level 3 concentration-response values, level 4 fit parameters, level 5 hit parameters, and level 6 flags for individual chemicals tested for given ‘AEIDs’, ‘m4ids’, ‘SPIDs’, or ‘DTXSIDs’.
Regular ToxCast/invitrodb users may find it easier to use tcpl, which has integrated ccdR’s bioactivity functions to make the API data retrievable in a familiar format. See the tcpl vignette regarding data retrieval via API for more information.
Functions
Several ccdR functions are used to access the CTX Bioactivity API data.
Bioactivity Assay Resource
Specific assays may be searched as well as all available assays that have data using two different functions.
Get annotation by aeid
get_annotation_by_aeid()
retrieves annotation for a
specific assay endpoint id (aeid).
aeid | assayComponentEndpointName | exportReady | internalReady | assayComponentEndpointDesc | assayFunctionType | normalizedDataType | burstAssay | keyPositiveControl | signalDirection | intendedTargetType | intendedTargetTypeSub | intendedTargetFamily | intendedTargetFamilySub | cellViabilityAssay | dataUsability | acid | assayComponentName | assayComponentDesc | assayComponentTargetDesc | parameterReadoutType | assayDesignType | assayDesignTypeSub | biologicalProcessTarget | detectionTechnologyType | detectionTechnologyTypeSub | detectionTechnology | keyAssayReagentType | keyAssayReagent | technologicalTargetType | technologicalTargetTypeSub | aid | assayName | assayDesc | timepointHr | organismId | organism | tissue | cellFormat | cellFreeComponentSource | cellShortName | cellGrowthMode | assayFootprint | assayFormatType | assayFormatTypeSub | contentReadoutType | dilutionSolvent | dilutionSolventPercentMax | asid | assaySourceName | assaySourceLongName | assaySourceDesc | gene | assayList | citations |
---|
aeid | assayComponentEndpointName | exportReady | internalReady | assayComponentEndpointDesc | assayFunctionType | normalizedDataType | burstAssay | keyPositiveControl | signalDirection | intendedTargetType | intendedTargetTypeSub | intendedTargetFamily | intendedTargetFamilySub | cellViabilityAssay | dataUsability | acid | assayComponentName | assayComponentDesc | assayComponentTargetDesc | parameterReadoutType | assayDesignType | assayDesignTypeSub | biologicalProcessTarget | detectionTechnologyType | detectionTechnologyTypeSub | detectionTechnology | keyAssayReagentType | keyAssayReagent | technologicalTargetType | technologicalTargetTypeSub | aid | assayName | assayDesc | timepointHr | organismId | organism | tissue | cellFormat | cellFreeComponentSource | cellShortName | cellGrowthMode | assayFootprint | assayFormatType | assayFormatTypeSub | contentReadoutType | dilutionSolvent | dilutionSolventPercentMax | asid | assaySourceName | assaySourceLongName | assaySourceDesc | gene | assayList | citations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
891 | CEETOX_H295R_11DCORT | 1 | 1 | Data from the assay component CEETOX_H295R_11DCORT was analyzed into 1 assay endpoint. This assay endpoint, CEETOX_H295R_11DCORT, was analyzed with bidirectional fitting relative to DMSO as the negative control and baseline of activity. Using a type of inducible reporter, gain or loss-of-signal activity using HPLC-MS-MS was used to understand synthesis of 11-Deoxycortisol in H295R cell line at 48hr of chemical exposure. To generalize the intended target to other relatable targets, this assay endpoint is annotated to the steroid hormone intended target family, where the subfamily is glucocorticoids. | detection of steroid hormone | log2_fold_induction | 0 | Prochloraz;Forskolin | bidirectional | molecular messenger | 11-Deoxycortisol | steroid hormone | glucocorticoids | 0 | 1 | 586 | CEETOX_H295R_11DCORT | CEETOX_H295R_11DCORT is one of 23 assay component(s) measured or calculated from the CEETOX_H295R assay. It is designed to make measurements of hormone induction, a form of inducible reporter, as detected with absorbance signals by HPLC-MS-MS technology. | single | inducible reporter | hormone induction | regulation of steroid hormone biosynthetic process | Spectrophotometry | Absorbance | HPLC-MS-MS | inducer | molecular messenger | 11-Deoxycortisol | 370 | CEETOX_H295R | CEETOX_H295R is a cell-based, multiplexed-readout assay that uses H295R, a human adrenal gland cell line, with measurements taken at 48 hours after chemical dosing in a 96-well plate. | 48 | 9606 | human | adrenal gland | cell line | H295R | adherent | microplate: 96-well plate | cell-based | cell-based format | multiplexed | DMSO | 0.1 | 8 | CEETOX | Ceetox/OpAns | Ceetox, a part of Cyprotex, is a Contract Research Organization (CRO) that in coordination with OpAns, an analytical laboratory, provide ADME-tox services. | [object Object] | [object Object] | [object Object] |
get_annotation_by_aeid_batch()
retrieves annotation for
a list (or vector) of assay endpoint ids (aeids).
Bioactivity Data Resource
There are several resources for retrieving bioactivity data associated with a variety of identifier types (e.g., DTXSID, aeid) that are available to the user.
Get summary data
get_bioactivity_summary()
retrieves a summary of the
number of active hits compared to the total number tested for both
multiple and single concentration by aeid.
aeid | activeMc | totalMc | activeSc | totalSc |
---|
aeid | activeMc | totalMc | activeSc | totalSc |
---|---|---|---|---|
891 | 178 | 576 | 233 | 2011 |
get_bioactivity_summary_batch()
retrieves a summary for
a list (or vector) of assay endpoint ids (aeids).
summary <- get_bioactivity_summary_batch(AEID = c(759,700,891))
summary <- data.table::rbindlist(summary)
aeid | activeMc | totalMc | activeSc | totalSc |
---|
aeid | activeMc | totalMc | activeSc | totalSc |
---|---|---|---|---|
759 | 153 | 8305 | ||
700 | 22 | 62 | 30 | 1077 |
891 | 178 | 576 | 233 | 2011 |
Get data
get_bioactivity_details()
can retrieve all available
multiple concentration data by assay endpoint id (aeid), sample id
(spid), Level 4 ID (m4id), or chemical DTXSID. Returned is chemical
information, level 3 concentration-response values, level 4 fit
parameters, level 5 hit parameters, and level 6 flags for individual
chemicals tested. An example for each request parameter is provided
below:
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | p | er | ga | tp | ac5 | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | bmdu | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | a | acc | flag | mc6MthdId |
---|
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | p | er | ga | tp | ac5 | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | bmdu | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | a | acc | flag | mc6MthdId |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
623 | 1833668 | TP0000904H05 | 45232 | 51-24-1 | Tiratricol | DTXSID2045232 | 4.208854513532483 | 29.9017719568567 | -7.501926040061633 | 29.9017719568567 | 1.301029995663981 | 29.9017719568567 | 1.301029995663981 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 2 | 173 | 5028314 | exp5 | 0.3882324490933417 | 15 | 25.2531270811949 | 2 | 1 | 20 | mM | uM | -0.6989700043360187,-1.698970004336019,1.301029995663981,0.3010299956639812,0.7781512503836436,-0.2218487496163564,-1.154901959985743,1.698970004336019 | 5.209938366718028,-4.959553158705701,29.9017719568567,-4.651386748844375,-7.501926040061633,-1.357858243451462,4.959553158705702,20.02118644067797 | 0.4433662313058135 | 0.9925644596727824 | 1721.526703551028 | 4025.726062922198 | 1149.786229757263 | 3865.930582986358 | 0.917722768672351 | 7.999998569591368 | 7.999999998725721 | 6.129949328588681 | 7.999999995602079 | 1.912545494391082 | 2.271387465068984 | 1.911407262331559 | 1.921797364752151 | 1.941838889601473 | 13.26328476638059 | 24.09270151565037 | 1.591995176195475 | 14.42814252864356 | 24.95752418383361 | 1.602022603368262 | 11.07501919056306 | 4057.25719300899 | 24.99533986136314 | 1.60202689770191 | 11.07620152627384 | 24.99533094420224 | 0.4304809360209948 | 1481.092471705383 | 3489.637064916511 | 63.54642686971948 | 1 | 9.110378433889926 | 21.53276777325637 | 0 | 65.7380627468674 | 13.46783082716225 | 63.5509972646931 | 1 | 9.128808609267953 | 21.51490015057924 | 65.56286926134463 | 1 | 9.029227555570293 | 21.46438223876761 | 62.98697633687659 | 1 | 8.155246492992447 | 24.09270151565037 | 58.33551786266656 | 1 | 5.064097391524118 | 24.95752418383361 | 62.50680467218653 | 1 | 5.12230318637964 | 24.99533979872922 | 58.50680471790864 | 1 | 5.12229712088364 | 24.99533094420224 | 1.911552655083965 | 1.910700897087612 | 1.30795225093553 | 24.87052311983435 | 0.7451572698575011 | 5.871582120667167 | 26000.97172895427 | 25.07762524984325 | 60411.57063986761 | 23.61210508379751 | 13.26328476638059 | 14.42814252864356 | 14.25725814782557 | 11.07501918362504 | 11.07620152627384 | 5.613227341543618 | 61.5465618387384 | 1 | 9.121069696481047 | 21.52404680104974 | 63.5566347758779 | 1 | 9.136999205494709 | 21.52535837501469 | 0.3503244451710362 | 0.3377543263851377 | 0.318983995045544 | 16.43765883183697 | 9.402421344167246 | 0.2866421065447428 | 10.811848496418 | 4.504679302336407 | 0.2889737774748023 | 4.654460027967879 | 4.624285420174428 | 0.1259128447672312 | 24.99999999999999 | 15244.34756919625 | 25.17656296791359 | 35357.40607056334 | 0.3376542920341601 | 0.3378939812942782 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4057.257196326073 | 7.999998569591368 | 1.591995176195475 | 14.42814252864356 | 24.95752418383361 | 10.4199297280811 | 13.39174000092412 | 7.920764280780008 | -25.16775893133328 | 24.95752418383361 | 11.40097409478228 | 12.52218953040614 | 14.42814252864356 | 6.346138919905622 | 16.86891434152304 | 5.064097391524118 | 12.81354489404794 | 0.02409708001933446 | 0.3882324490933417 | 0.9882944042371128 | Borderline,Average number of replicates per conc is less than 2,Multiple points above baseline, inactive | 11,13,8 | |||||||||||||
626 | 1834094 | TP0000904H05 | 45232 | 51-24-1 | Tiratricol | DTXSID2045232 | 4.884792210388105 | 29.6569605105704 | -0.8775428799361791 | 29.6569605105704 | 1.301029995663981 | 29.6569605105704 | 1.301029995663981 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 2 | 127 | 5028740 | exp4 | 0.01954693088289667 | 13 | 29.30875326232863 | 2 | 1 | 20 | mM | uM | -1.154901959985743,1.698970004336019,0.7781512503836436,-0.2218487496163564,-1.698970004336019,1.301029995663981,0.3010299956639812,-0.6989700043360187 | -0.8775428799361791,14.81850817710411,7.818109293976865,0.6182688472277631,0.8775428799361791,29.6569605105704,14.00079776625449,11.22856003191065 | 6.104769005070028 | 0.3000006170210526 | 2626.481774292507 | 6939.137998405839 | 120.1571107791539 | 23397.7652944306 | 0.3000003169877059 | 0.594894190079819 | 0.8731492533237095 | 7.968128567118133 | 0.699837429056946 | 1.733524844614035 | 2.380613185122028 | 2.060944039839989 | 1.854638011717502 | 1.742284415011934 | 2.819397502264771 | 19.00752360680906 | 1.697838367522549 | 1.692786680000895 | 18.11557823124747 | 1.63278254415198 | 1.735452996784926 | 54.87984244327055 | 24.19390328229074 | 1.693847604831058 | 1.813379328743659 | 19.44068645643118 | 0.3798457805281215 | 2264.108194081772 | 6022.235022571993 | 60.00263716196596 | 1 | 6.885998407649498 | 19.7406425723923 | 0 | 66.57834307933227 | 13.6210849518058 | 65.81071829753414 | 1 | 10.22892676304634 | 18.99347662794126 | 62.2288005070792 | 1 | 6.886283476321515 | 20.58121443270486 | 59.58183045768615 | 1 | 6.490262952004159 | 19.00752360680906 | 60.9304013944322 | 1 | 6.304211108274938 | 18.11557823124747 | 64.01083808276202 | 1 | 5.921058456285511 | 22.15886707286351 | 61.05594929038858 | 1 | 6.438553620903468 | 19.44068645643118 | 2.059622051495357 | 2.060557788977562 | 3.149959838854599 | 4.960651860666694 | 0.1482676079125486 | 7.091261826118074 | 30938.21312122273 | 25.04503431464244 | 81312.38225224172 | 303.1118237953914 | 5.644138602314242 | 141170.2663754508 | 0.1778352437319646 | 2.819397502264771 | 1.692786680000895 | 0.4013547630918278 | 1.430673037314812 | 1.813379328743659 | 0.6752166489168941 | 63.80340730003342 | 1 | 10.22362919651012 | 18.99228902640607 | 65.82009863445656 | 1 | 10.23868873008271 | 18.95397715159491 | 0.3335635504694223 | 0.3494704187545203 | 0.34371770733318 | 0.3221439177850666 | 4.969271064671941 | 7.484672815601464 | 0.3208267776910146 | 2.257955931218438 | 5.794590169915659 | 0.3258697289486165 | 3.80561876348739 | 9.540592027517304 | 0.160075249411384 | 25 | 17871.43826386584 | 25.10292576027813 | 47059.40366080807 | 0.3493877366290281 | 0.3495083063258392 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 55.42854487892154 | 1.742284415011934 | 2.819397502264771 | 19.00752360680906 | 0.2086370544887254 | 2.8461708745718 | 9.56611220343328 | -26.79091522884307 | 19.00752360680906 | 0.4285571419954925 | 0.9076432666342852 | 2.819397502264771 | 0.4238114773232821 | 10.47832405134898 | 6.490262952004159 | 1.899255719797609 | 0.02936188472122571 | 0.01954693088289667 | 0.6485271972056202 | Average number of replicates per conc is less than 2,Multiple points above baseline, inactive,Bmd > ac50, indication of high baseline variability | 13,8,9 | ||||||||||
645 | 1836233 | TP0000904H05 | 45232 | 51-24-1 | Tiratricol | DTXSID2045232 | 3.426557268776339 | 7.386363636363637 | -9.09090909090909 | 7.386363636363637 | 1.698970004336019 | 7.386363636363637 | 1.698970004336019 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 0 | 134 | 5030879 | poly1 | 0.00004481617968402787 | 13 | 20.55934361265804 | 2 | 1 | 20 | mM | uM | 0.7781512503836436,-1.698970004336019,-1.154901959985743,-0.6989700043360187,-0.2218487496163564,1.301029995663981,0.3010299956639812,1.698970004336019 | -7.702020202020201,2.904040404040405,-2.904040404040403,-0.9469696969696955,-8.143939393939391,-3.598484848484848,-9.09090909090909,7.386363636363637 | 7.38792442803479e-8 | 4.707344288793977 | 9.720535659483423e-7 | 3.155293427742727 | 10.99247530891463 | 54.33735479981147 | 7.997291932162272 | 7.999998484010299 | 7.999999892071809 | 2.960700330936843 | 7.99999611469226 | 1.563512627809527 | 1.719984746193826 | 1.559108936230694 | 1.559419875600755 | 1.688392041373899 | 74.80480041333628 | 8.863636346356905 | 1.56077445822989 | 44.41766078913898 | 8.863603105060312 | 1.561195254781372 | 41.16217714273171 | 1968.426178452086 | 8.863620744215016 | 1.561541834840503 | 41.13429235835103 | 8.85885765273257 | 0.0916727261027705 | 0.00003275646438816725 | 0.1108482935333661 | 56.80252966886766 | 1 | 5.474106464958057 | 7.347831543130136 | 0 | 54.82949934043421 | 6.057646057469498 | 56.76807692440605 | 1 | 5.465880012590823 | 7.407786706660837 | 58.76914315577856 | 1 | 5.466134248427126 | 7.388890198629367 | 58.3862013644993 | 1 | 5.91931768956607 | 8.863636346356905 | 58.77145121585644 | 1 | 5.466684000894818 | 8.863603105060312 | 62.77764470962573 | 1 | 5.468147134258676 | 8.859894820651965 | 58.77767023528245 | 1 | 5.468153598929289 | 8.85885765273257 | 1.670818834303433 | 1.603520396966836 | 0.000001480451506031931 | 43.15399398938185 | 0.148714056473758 | 9.788806432103662 | 0.00000229547866974318 | 47.81291767075994 | 0.1144483227925822 | 46.54017033404035 | 74.80480041333628 | 44.41766078913898 | 30.83791719208217 | 41.15796107500761 | 20.62365118253162 | 917.2489266479544 | 41.13429235835103 | 20.75516715187462 | 56.20208741239672 | 1 | 5.879174343453156 | 4.583636305138524 | 57.24725841856889 | 1 | 5.591373578271515 | 6.679450797669966 | 0.3147662275887214 | 0.3149423684604092 | 0.3050999358871871 | 206.2390399498295 | 24.86638414047322 | 0.3151258300122656 | 133.054428596896 | 82.18120992121477 | 0.3151960563959714 | 64.74140517770995 | 2232417.631488272 | 23.21626426125372 | 0.3152310297032542 | 66.03127922964485 | 23.58531159693002 | 0.1010593993678142 | 25 | 0.000828471087305424 | 35.33912739968434 | 1.405231606381962 | 0.3056358969644425 | 0.31148611469958 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1968.985213635597 | 1.670818834303433 | 2.5 | 144.0461131493368 | 13.20509987690784 | -26.10104370619836 | 4.583636305138524 | 5 | 10 | 25 | 52.7459473602489 | 5.879174343453156 | 106.7799207926885 | 0.6651420101678049 | 0.00004481617968402787 | 0.2229466266771502 | 0.0916727261027705 | Average number of replicates per conc is less than 2,Bmd > ac50, indication of high baseline variability | 13,9 | ||||||||||
647 | 1836494 | TP0000904H05 | 45232 | 51-24-1 | Tiratricol | DTXSID2045232 | 2.872463281346044 | 24.5911214953271 | -15.3441768511862 | 24.5911214953271 | -0.6989700043360187 | 24.5911214953271 | -0.6989700043360187 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 1 | 176 | 5031140 | poly1 | 0.0007691234876598405 | 13 | 20 | 2 | 1 | 20 | mM | uM | -0.2218487496163564,-1.154901959985743,-1.698970004336019,1.698970004336019,0.3010299956639812,-0.6989700043360187,1.301029995663981,0.7781512503836436 | 0.3100287562904382,-4.23705966930266,4.23705966930266,-10.65330697340043,-15.3441768511862,24.5911214953271,-3.338425593098491,4.084291876347951 | 0.000001533358625150776 | 0.3766871063745604 | 0.000001193669392375298 | 75.25835790295875 | 0.0006569488939842799 | 96.83528802743167 | 7.800663857633126 | 7.937542044894579 | 0.729162061739079 | 7.999999989113995 | 7.874824062203916 | 2.14936705216903 | 2.149647244900154 | 2.149931442577875 | 2.150315520704397 | 2.149639800584959 | 19.43454346215864 | 1.134171359250443e-9 | 2.149683383706944 | 116.5095827986136 | 0.00240332207823058 | 2.16232385103293 | 0.01495165189302865 | 0.4728127504187675 | 11.2206197033088 | 2.149646216342116 | 158.0672323783486 | 0.09087731268651236 | 1.251097577399308e-9 | 0.00001062228285978774 | 65.91494218290552 | 67.2883088418402 | 1 | 11.2776777996436 | 0.000006693046390825522 | 0 | 63.28830594767818 | 11.27767685403318 | 67.2883069898754 | 1 | 11.27767700055377 | 0.000001125966247592959 | 69.28831082872938 | 1 | 11.27767730254966 | 0.000003797491381994292 | 67.28830594801778 | 1 | 11.2776768541672 | 1.134171359250443e-9 | 69.2883064884335 | 1 | 11.2776770925602 | 0.00240332207823058 | 72.17919094570237 | 1 | 9.771294007073369 | 9.896104475278875 | 69.28830869470625 | 1 | 11.2776780964788 | 0.09087731268651236 | 2.149685142436541 | 2.148966138658335 | 7.939966888042317 | 10.10441398053766 | 29.07816874655387 | 45.7572447748528 | 19.43454346215864 | 116.5095827986136 | 0.01079980647197256 | 158.0672323783486 | 65.28830598103433 | 1 | 11.2776768623634 | 6.255487886996541e-8 | 67.28831401939081 | 1 | 11.27767868258289 | 0.00001416966355093649 | 0.4105028884852779 | 25 | 30.16200653088329 | 0.6280287466170111 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0.4784752591912469 | 2.149685142436541 | 2.5 | 10895116980.46777 | 13.6308544597453 | -30.64415299051716 | 6.255487886996541e-8 | 4.999999999999999 | 9.999999999999998 | 25 | 86.00840841895133 | 11.2776768623634 | 8076439570.398645 | 0.7310585819091135 | 0.0007691234876598405 | 3.12774394349827e-9 | 1.251097577399308e-9 | Average number of replicates per conc is less than 2,Bmd > ac50, indication of high baseline variability | 13,9 | ||||||||||||||||||||||||||||||||||||
679 | 1839401 | TP0000904H05 | 45232 | 51-24-1 | Tiratricol | DTXSID2045232 | 5.621579363521706 | 14.08123821744849 | -6.612486732252886 | 14.08123821744849 | 0.3010299956639812 | 14.08123821744849 | 0.3010299956639812 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 0 | 133 | 5034047 | exp4 | 3.719643282937537e-15 | 13 | 33.72947618113024 | 2 | 1 | 20 | mM | uM | -1.698970004336019,0.3010299956639812,-1.154901959985743,0.7781512503836436,-0.2218487496163564,-0.6989700043360187,1.301029995663981,1.698970004336019 | 2.278091979151815,14.08123821744849,-2.278091979151814,-6.612486732252886,10.67915023050235,13.08952362847142,4.467468276222602,6.318616035359553 | 2.240045406368432 | 0.3000004994310594 | 112.9808307298245 | 865.8254929535174 | 4.545028620685052 | 65.7285988399926 | 0.3000003150791311 | 7.999999018346869 | 0.300091098903469 | 7.550849029707361 | 0.3000000001722775 | 1.908432603296563 | 2.050383693644464 | 1.951409270215791 | 1.920376769986231 | 1.675454930244296 | 0.07329301415768419 | 7.710786101521187 | 1.513226499207291 | 0.1453438995327829 | 8.610190191604286 | 1.847019846769863 | 0.2923163116513761 | 59.66977501585602 | 9.655899171708228 | 1.882783861146438 | 54.87345686534822 | 16.84192180335446 | 0.1342723480805489 | 163.9460467931164 | 1270.052464079879 | 62.22501034060233 | 1 | 7.635077607201984 | 7.243503453530403 | 0 | 60.31637953410401 | 8.643268453824428 | 63.20845198455855 | 1 | 8.236056037957985 | 6.716525076559469 | 64.52332339400041 | 1 | 7.810212289193087 | 6.873721691967609 | 59.07676009097395 | 1 | 6.585985949819935 | 7.710786101521187 | 59.34963698633271 | 1 | 6.313571586200532 | 8.610190191604286 | 66.68700367035977 | 1 | 7.005486126644505 | 7.69073998343443 | 63.70370651182299 | 1 | 7.371748953581798 | 16.84192180335446 | 1.951416089168986 | 1.953269884448892 | 4.960647368144271 | 9.193701942255004 | 2618.100047268923 | 25.36087709286901 | 19534.17746336956 | 9.693473276544648 | 0.07329301415768419 | 0.1453438995327829 | 21.25760832645036 | 0.07386566609090593 | 54.87345686534822 | 61.20659443782829 | 1 | 8.235017480262172 | 6.713617404027446 | 63.20908399331483 | 1 | 8.236417282123691 | 6.708398029005737 | 0.3217657962416384 | 0.3229019384511885 | 0.07925814316759382 | 2.776801163350604 | 0.3377590868121545 | 0.1497221856945271 | 2.407155897719999 | 0.1170799344111758 | 25 | 3437.347970091856 | 25.4732963329731 | 25758.50715822951 | 0.3217981005030134 | 0.3219086993548163 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 60.3477904963023 | 1.675454930244296 | 0.07329301415768419 | 7.710786101521187 | 0.005423725663435604 | 12.402303920102 | -26.53838004548697 | 7.710786101521187 | 0.01114076487987984 | 0.02359508041633574 | 0.07329301415768419 | 6.585985949819935 | 0.3498247285223899 | 3.719643282937537e-15 | 0.2286067551157211 | Average number of replicates per conc is less than 2 | 13 | |||||||||||||||||||||||||
704 | 1842443 | TP0000904H05 | 45232 | 51-24-1 | Tiratricol | DTXSID2045232 | 3.763467929968328 | 5.412234762165331 | -10.497225111687 | 5.412234762165331 | -0.6989700043360187 | 5.412234762165331 | -0.6989700043360187 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 0 | 42 | 5037089 | poly1 | 0.000001311151554840566 | 13 | 22.58080757980996 | 2 | 1 | 20 | mM | uM | 0.7781512503836436,1.301029995663981,-0.6989700043360187,-1.698970004336019,1.698970004336019,-0.2218487496163564,0.3010299956639812,-1.154901959985743 | -10.497225111687,-8.271301702212094,5.412234762165331,-0.5697089223331855,-5.410731572396609,-1.152645914630851,-9.935332776150975,0.5697089223331855 | 5.868021963410569e-8 | 0.310104699274879 | 0.00000820221770260021 | 63.67412912081 | 0.00001510015468926551 | 66.7682650559194 | 4.045012130124175 | 2.518456690085134 | 1.004146220375644 | 7.988324375445398 | 2.638717782813107 | 1.748991997794754 | 1.749320687470586 | 1.750258491333818 | 1.749432399489879 | 1.749309764365863 | 3.343289162141123 | 3.712554221824454e-10 | 1.749311182417269 | 3.185722315810508 | 5.594093755272163e-10 | 1.716545656364157 | 0.01570664001062715 | 0.4966875709539269 | 2.580846160887361 | 1.749345944481645 | 33.73657111465509 | 4.159714315410043e-9 | 2.671599719093895e-11 | 0.000005233244887677393 | 60.3011801386689 | 59.65799055310836 | 1 | 6.498682968118529 | 1.974014384265886e-7 | 0 | 55.65798921703397 | 6.498682892070479 | 59.65800315845096 | 1 | 6.498684604595836 | 0.000009784846486708034 | 61.65799122389731 | 1 | 6.498683482667944 | 0.00000549637162559571 | 59.65798921968127 | 1 | 6.498682892244033 | 3.712554221824454e-10 | 61.65798921951322 | 1 | 6.498682892347669 | 5.594093755272163e-10 | 65.24298472190893 | 1 | 6.371147760432374 | 2.422030692633518 | 61.65798922272976 | 1 | 6.498682892532436 | 4.159714315410043e-9 | 1.74933846970414 | 1.749869269967504 | 5.348516727471637 | 6.885946392795786 | 29.78666140201014 | 42.90853049989956 | 3.343289162141123 | 3.185722315810508 | 0.01389270927392189 | 33.73657111465509 | 57.65798921945516 | 1 | 6.49868289233687 | 1.335799859546947e-9 | 59.65799619491047 | 1 | 6.498684235032681 | 0.000007937241563467504 | 0.3237947062807544 | 25 | 30.40176401368837 | 0.7320994661619505 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0.5007494385640836 | 1.74933846970414 | 2.5 | 347699605501.9814 | 9.289141683881516 | -26.82899460972758 | 1.335799859546947e-9 | 4.999999999999999 | 9.999999999999998 | 25 | 108.3553281419698 | 6.49868289233687 | 257746186435.8647 | 0.7310585788680222 | 0.000001311151554840566 | 5.915642542126427e-11 | 2.671599719093895e-11 | Bmd > ac50, indication of high baseline variability,Average number of replicates per conc is less than 2 | 9,13 |
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | a | er | ac5 | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | flag | mc6MthdId |
---|
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | a | er | ac5 | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | flag | mc6MthdId |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
891 | 739695 | TP0001055F12 | 20182 | 80-05-7 | Bisphenol A | DTXSID7020182 | 0.09919961779770327 | 0.2791188509977269 | -0.1881068333338392 | 0.1676119338196913 | -0.3979400086720376 | 0.1676119338196913 | -0.3979400086720376 | 1 | -1.397940008672037 | 6 | 11 | 2 | 0 | 188 | 5593410 | poly1 | 9.810625094754254e-8 | 13 | 0.5951977067862196 | 2 | 0 | 100 | mM | uM | -0.3979400086720376,-1,-0.3979400086720376,-1,-1.397940008672037,0.4771212547196624,1,0,1,-1.397940008672037,0 | 0.0561050166416558,0.00282433403658312,0.2791188509977269,0.09964190007975987,-0.05239317472308807,0.1364891493912145,-0.1389434932540333,0.1057692224906191,-0.1881068333338392,-0.1264330324885036,0.226491395765047 | -1.041990145274811e-9 | 8.195719468765455 | -0.000008020657993646346 | 1.0081488305683 | -0.1785159155944527 | 10.55654958362652 | 7.948369436376844 | 7.999984090641454 | 7.999999433512889 | 7.999999868358701 | 7.999989876076246 | -2.224154127442925 | -2.009262774570018 | -2.225708040123303 | -2.224425887819182 | -2.124036451537194 | 0.1179271250070959 | 0.08489455573191221 | -2.171779858456515 | 0.09852824789221568 | 0.09435469694399896 | -2.409215721065098 | 0.110735916336773 | 3.615988007373274 | 0.1667107900647192 | -2.172018605109454 | 0.09803353623010123 | 0.09440072781239386 | -0.01306873535960684 | -5.269417957001975e-7 | 0.01831376663143582 | -6.832650945946463 | 1 | 0.132132009678528 | -0.1635245943122368 | 0 | -7.147369971314445 | 0.1494006788346007 | -6.828917132671787 | 1 | 0.1321494981100909 | -0.1629406985095443 | -4.832659756139471 | 1 | 0.1321319750928946 | -0.1635026819836897 | -4.925185522837284 | 1 | 0.141419005660482 | 0.08489455573191221 | -3.632093295281366 | 1 | 0.1390269972952649 | 0.09435469694399896 | -5.940065751343273 | 1 | 0.1001420603491322 | 0.1667104968137298 | -3.631378898610976 | 1 | 0.1390355254673785 | 0.09440072781239386 | -2.136507706280431 | -2.206000847538158 | 8.064774993426964e-7 | 9.189033846549512 | 0.1852212916491659 | 0.1818331859183672 | 0.000005089896402909899 | 9.301254102363394 | 0.056465976982944 | 3.979003442587248 | 9.337383425640624 | 27.39660744801847 | 129.2583959018016 | 0.1179271250070959 | 0.09852824789221568 | 41.93495641250747 | 0.1107358676217389 | 34.65357457194307 | 22.96654142812522 | 0.09803353623010123 | 34.01111635735984 | -7.127002748688808 | 1 | 0.1411355628562584 | -0.1306873535960684 | -6.451941535337074 | 1 | 0.1339787393553211 | -0.1573989840882838 | 0.2759427726798687 | 0.2757016914770977 | 0.275900255733028 | 0.2776340911881771 | 0.1562203377069493 | 0.06103845273627646 | 0.2828948492106326 | 0.0308902358522886 | 0.0576805352571672 | 0.2593751756378341 | 0.05646638780675963 | 2.387358256194306 | 0.05570893358002292 | 0.2828774339235875 | 0.04329238363253893 | 0.05763006648910211 | 0.007769845359223608 | 5 | 0.000001423027196013611 | 7.068388784616721 | 0.004146833085610651 | 0.2737044785697688 | 0.2761542494416785 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3.615989598330573 | -0.01306873535960684 | -2.136507706280431 | 0.5000000000000001 | 18.76944945736944 | 0.2452929678038774 | 5.563501374344404 | -0.1306873535960684 | 1 | 2 | 5 | 9.512878425240512 | 0.1411355628562584 | 13.91360226639691 | 0.5025458808263291 | 9.810625094754255e-8 | 0.2195696524130058 | Bmd > ac50, indication of high baseline variability | 9 |
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | p | er | ga | tp | ac5 | acc | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | bmdu | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | flag | mc6MthdId |
---|
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | p | er | ga | tp | ac5 | acc | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | bmdu | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | flag | mc6MthdId |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3094 | 822141 | ES211_47_47 | 944145 | 21535-47-7 | Mianserin hydrochloride | DTXSID30944145 | 6.75211217879369 | 101.9748906816005 | -5.852474808193342 | 101.28943947387 | 2.301029995663981 | 101.164780328344 | 2.301029995663981 | 2.301029995663981 | -6 | 9 | 36 | 4 | 3 | 42 | 7598924 | exp5 | 0.9999999999966847 | 42 | 20.25633653638107 | 2 | 1 | 100 | -0.3010299956639812,-3,2.301029995663981,1.903089986991944,0.6989700043360189,0.6989700043360189,-1.301029995663981,-6,2.301029995663981,1.477121254719662,1,1.477121254719662,1,-1.301029995663981,-0.3010299956639812,-3,-6,1.903089986991944,1.903089986991944,1,1.477121254719662,-0.3010299956639812,0.6989700043360189,-1.301029995663981,-3,2.301029995663981,1.477121254719662,1.903089986991944,0.6989700043360189,-0.3010299956639812,-1.301029995663981,-6,2.301029995663981,-6,1,-3 | 7.427232859032931,-3.750051787305786,101.0730722839644,98.9002717861462,17.02699226830727,17.6998058508645,2.996494120121969,-2.341837802946403,100.8533065571916,58.64570278003023,5.964872358375655,49.11565073337273,14.83512968293488,-3.97552512509284,8.861038251024265,-2.503018132836884,10.01979188930157,99.31356213766618,101.3930578199261,19.77117858122105,52.08497346996094,6.965386514618434,12.3375288848155,-5.852474808193342,2.4837211637883,101.2564883727236,45.27350419250797,101.2564883727236,10.37341293755662,8.43972728547434,-3.987565892079643,1.769331584793483,101.9748906816005,14.29629611001132,6.899162035880055,-0.9777667971902465 | 8.980263423505296 | 0.4658605032164628 | 20906.92044366298 | 38271.29349651447 | 1485.951434389736 | 65459.19750014387 | 0.4615703010451145 | 1.459813726340486 | 2.088229294094074 | 7.993467618938603 | 2.08823290079987 | 2.153005726183071 | 3.559225994976655 | 2.699502970424646 | 2.160074386736033 | 1.794478890003238 | 28.42183560284198 | 105.3584960352699 | 1.632386071051454 | 29.1363046349495 | 102.8619485053671 | 1.785265345147171 | 29.22448841589741 | 3787.921673603752 | 106.4048094182663 | 1.785256872105232 | 29.22430650665218 | 106.4045029407132 | 0.5474828009413533 | 27146.76160052323 | 49818.73895889866 | 286.2961627225351 | 1 | 12.74928808443735 | 105.9858941214046 | 0 | 384.3251737754444 | 51.11462615866245 | 328.2752622937805 | 1 | 23.28731820786984 | 109.5423855168188 | 288.7695452039763 | 1 | 12.85397625786147 | 106.233987344086 | 252.1509683687774 | 1 | 7.153206032224669 | 105.3584960352699 | 242.3781899636461 | 1 | 6.04671272377595 | 102.8619485053671 | 256.4328714022909 | 1 | 6.883032818734613 | 106.3485222050823 | 252.4328714115678 | 1 | 6.883035058943881 | 106.4045029407132 | 2.698231249887153 | 2.69823328798644 | 1.645987076206435 | 45.16993304352483 | 0.0359070833296379 | 13.17746336166956 | 80054.91579295504 | 100.1306460757878 | 146042.5963422222 | 1557.21080934484 | 46.23219211065147 | 126993.039276333 | 0.04175006048618471 | 28.42183560284198 | 29.1363046349495 | 0.1607743174464076 | 29.20968584167239 | 29.22430650665218 | 0.3854703745468205 | 326.2063457159531 | 1 | 23.26633589778075 | 109.4965601882707 | 328.3117909623189 | 1 | 23.31262758064483 | 109.4196453013442 | 0.1758881195751216 | 0.1841408553743498 | 0.1761656047704497 | 0.1495153767425872 | 2.504500211345132 | 3.090966159056836 | 0.1494114951654834 | 1.684064887529466 | 2.136108342287016 | 0.1483256759099089 | 1.96787729051603 | 3.504225659847863 | 0.03918729131429517 | 100 | 84355.29653483114 | 100.1999242731534 | 154185.5682593887 | 0.1840572310279764 | 0.1841144889854715 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3788.386357352186 | 1.459813726340486 | 1.632386071051454 | 29.1363046349495 | 102.8619485053671 | 4.895974620693649 | 13.24600243131853 | 11.99450775608619 | 17.77639807489224 | -117.1890949818231 | 102.8619485053671 | 8.01655754617927 | 13.40417212394662 | 29.1363046349495 | 11.03986268985668 | 12.96307264803177 | 6.04671272377595 | 9.600739034050022 | 1.501772349462315e-31 | 0.9999999999966848 | 5.078013406847952 | |||||||||||
3098 | 822345 | ES211_47_47 | 944145 | 21535-47-7 | Mianserin hydrochloride | DTXSID30944145 | 6.292361272058492 | 98.60944617597698 | -15.48789259170463 | 97.61114262807376 | 2.301029995663981 | 97.67386193907646 | 2.301029995663981 | 2.301029995663981 | -6 | 9 | 36 | 4 | 3 | 42 | 7599128 | exp5 | 0.9999999999589282 | 42 | 18.87708381617547 | 2 | 1 | 100 | -6,1.477121254719662,-1.301029995663981,-3,1.903089986991944,1.903089986991944,1.477121254719662,-0.3010299956639812,0.6989700043360189,-1.301029995663981,-3,2.301029995663981,1.477121254719662,0.6989700043360189,-0.3010299956639812,-1.301029995663981,-6,2.301029995663981,1,-3,0.6989700043360189,1.477121254719662,-0.3010299956639812,-3,2.301029995663981,1.903089986991944,1,0.6989700043360189,-1.301029995663981,2.301029995663981,1.903089986991944,1,1,-0.3010299956639812,-6,-6 | -15.48789259170463,40.44593622632463,-3.308559098537521,2.48718910136233,95.05061867266592,94.2402094469292,41.22395549252754,13.28583927009124,12.40318533871496,5.966930265995686,3.259046249700456,97.74742391564821,37.58280214973128,13.20393002635993,1.865386713210429,7.428820770153813,-0.5751258087706687,96.48740045816517,10.04690738518599,6.577942620268354,0.2397506593143131,45.62664749580637,10.74082953728123,3.47638456005754,98.60944617597698,96.61951570366818,36.84967633660992,25.08436445444319,14.13573303337083,97.60029996250469,94.17685118619698,5.586801649793776,16.46297627606039,6.709801102324467,-0.6374203224596925,4.330751609032399 | 8.718852311483452 | 0.4621192452087188 | 30733.63862806683 | 58053.22582237376 | 95.1637174921906 | 487.2146854984712 | 0.3644894906709538 | 1.592160711743204 | 2.500615106666126 | 7.884701749657575 | 2.500561580345472 | 2.138668710573835 | 3.513038616419502 | 2.697028969994061 | 2.218574492106437 | 2.011051198182322 | 32.650308081937 | 102.3561768059361 | 1.748232815338749 | 33.60823929102817 | 99.05623958289912 | 1.871234980860722 | 33.56038699307263 | 5782.338770572877 | 101.4481585834202 | 1.87122007584661 | 33.56045811387879 | 101.4484696652948 | 0.5305416047533859 | 27673.0817955942 | 52368.24882950644 | 284.1191487968616 | 1 | 12.16774614719956 | 100.8810435335372 | 0 | 380.5440532323087 | 48.52148017787647 | 324.7773127348888 | 1 | 21.59635686848189 | 106.0634942814029 | 288.1657847448681 | 1 | 12.65470515074108 | 100.9041370315749 | 266.6070682545724 | 1 | 8.542515933428906 | 102.3561768059361 | 257.6591381302885 | 1 | 8.397684028922718 | 99.05623958289912 | 269.9181398445775 | 1 | 9.43263682314636 | 101.4381506739147 | 265.9181398398791 | 1 | 9.432603290521724 | 101.4484696652948 | 2.697415087555964 | 2.697491002862335 | 1.653268081419588 | 44.62909211616844 | 0.0376325456433776 | 13.014601637003 | 144770.5293351298 | 100.0861278155846 | 273004.744141002 | 144.7420328215297 | 46.69029054309706 | 1335.788054548118 | 0.09938750851619732 | 32.650308081937 | 33.60823929102817 | 0.1861700465060868 | 33.55773915040644 | 33.56045811387879 | 0.6962069108870773 | 322.7320181754561 | 1 | 21.57668897283424 | 106.1083209506772 | 324.8320043418396 | 1 | 21.61297536454886 | 106.0901172201991 | 0.172010361246493 | 0.1724789031231027 | 0.1778243849070398 | 0.1481673853731173 | 3.880010286094815 | 3.881300977472912 | 0.166758575774621 | 1.909160862868152 | 2.442228657418365 | 0.1680733185213183 | 1.963091911442781 | 4.0603354568457 | 0.03909925746514938 | 100 | 88278.60946926908 | 100.190228208773 | 166328.9016942867 | 0.1724632539360627 | 0.1725193110812217 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 5782.479713707603 | 1.592160711743204 | 1.748232815338749 | 33.60823929102817 | 99.05623958289912 | 6.549950475444407 | 15.94280165636692 | 15.15768602592679 | 17.55669760831705 | -124.8295690651443 | 99.05623958289912 | 10.29403978104101 | 16.49226434079241 | 33.60823929102817 | 13.9632920083894 | 16.36542533906654 | 8.397684028922718 | 12.35337480282101 | 2.069568144836631e-27 | 0.9999999999589282 | 5.24743337199252 | |||||||||||
3095 | 1150437 | ES211_47_47 | 944145 | 21535-47-7 | Mianserin hydrochloride | DTXSID30944145 | 0.1635842394403502 | 11.45832139758188 | 0.04981319925745456 | 4.937025241580714 | 1.903089986991944 | 5.454860652403362 | 1.903089986991944 | 2.301029995663981 | -6 | 9 | 36 | 4 | 2 | 42 | 7598992 | exp5 | 0.9999998831449819 | 42 | 0.4907527183210506 | 2 | 1 | 100 | -0.3010299956639812,-1.301029995663981,2.301029995663981,0.6989700043360189,-0.3010299956639812,-6,2.301029995663981,1,-3,0.6989700043360189,1.477121254719662,-0.3010299956639812,-3,2.301029995663981,1.903089986991944,1,0.6989700043360189,-1.301029995663981,-6,2.301029995663981,1.477121254719662,1.903089986991944,1,1,-1.301029995663981,-0.3010299956639812,-3,-6,1.903089986991944,-6,1.903089986991944,1.477121254719662,0.6989700043360189,-3,1.477121254719662,-1.301029995663981 | 0.2882675039415536,0.2293577923201378,2.12765731100286,0.2760905500803271,0.2223210266269225,0.2859185064112817,3.726705759810087,0.169779282809137,0.2335357255129443,0.3364575742259655,0.2644336595666082,1.101262393197357,0.4222553297999173,1.724134958388003,6.3829741964722,0.1518602827691616,0.500500483800451,0.4657932906610395,0.6850736830999858,11.45832139758188,0.362318825993606,4.526747108334523,0.2382843463520162,0.22948937953272,0.3481086018076444,0.3596198212273357,0.461420136851573,0.5216095250469567,6.565653249670075,0.2280501658369403,2.272726411846056,0.3340757114300033,0.04981319925745456,0.222937819595298,0.4805766727842742,0.1649776062932452 | 0.07306340900696351 | 0.6909308897469263 | 489.2545647399257 | 30770.89549405515 | 16.86144381389201 | 2819.131595534077 | 0.6927530157131045 | 4.565817027769467 | 7.955761313099027 | 0.5644747159243586 | 7.999999975199726 | -0.4956759683416578 | -0.06367288253941095 | -0.4920846292443089 | -0.4952315996998395 | -0.487808185784333 | 62.93659357259897 | 3.160545685691406 | -0.5427393909605482 | 45.24973438082952 | 3.609271629758298 | -0.5743685279270239 | 40.39441528906965 | 1277.383571744619 | 4.974388239825092 | -0.5418420584767905 | 39.36283274277378 | 3.598558047969296 | 0.01595125875398246 | 689.1656998074085 | 43422.63584041456 | 119.2711022611793 | 1 | 1.970612708065348 | 2.841532541460785 | 0 | 147.0232023167763 | 2.721308026038458 | 121.536640649848 | 1 | 1.980607019686624 | 3.190339433218957 | 121.4157041034835 | 1 | 1.964500358062248 | 2.924533593711578 | 117.4064956966718 | 1 | 1.91439148753269 | 3.160545685691406 | 108.6937106313571 | 1 | 1.583968874488692 | 3.609271629758298 | 110.2353134814215 | 1 | 1.540743257946914 | 4.114035106463596 | 108.7802965738098 | 1 | 1.587007331906058 | 3.598558047969296 | -0.4932227568303567 | -0.4931857994848398 | 0.06098198965840179 | 73.34025784745266 | 0.1766430905575937 | 0.8923597763803547 | 3184.620201561832 | 100.1624909226241 | 199490.5906912948 | 58.61911836048125 | 77.81121531926684 | 9986.108641207353 | 0.2968322070200219 | 62.93659357259897 | 45.24973438082952 | 4.213044861329193 | 39.82732298572839 | 39.36283274277378 | 5.573024297626113 | 119.5128529478745 | 1 | 1.9801146542527 | 3.190251750796493 | 121.5464018003153 | 1 | 1.981069269414523 | 3.188843374662825 | 0.1987585962525786 | 0.1966979702020276 | 0.1972498561659399 | 0.1965661043023219 | 34.81821712492219 | 1.039039565244225 | 0.1840458110753714 | 16.99176937771065 | 0.663162309702829 | 0.1839256971283731 | 7.865147277595785 | 0.6707173101135189 | 0.003422826182028237 | 100 | 3794.628359530953 | 100.2292375794687 | 237831.7025456579 | 0.1965936372150349 | 0.196607292096659 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2372.257028446487 | 4.565817027769467 | -0.5427393909605482 | 45.24973438082952 | 3.609271629758298 | 25.58333819273506 | 32.1774799249858 | 40.2421510325514 | 1.203793338337098 | -50.34685531567855 | 3.609271629758298 | 29.9520321053751 | 35.30253965284071 | 45.24973438082952 | 33.26444641037514 | 53.79376393388814 | 1.583968874488692 | 37.21757330690621 | 4.751783349020907e-9 | 0.999999883144982 | 7.354562685065171 | Noisy data | 10 | |||||||||
3096 | 1150505 | ES211_47_47 | 944145 | 21535-47-7 | Mianserin hydrochloride | DTXSID30944145 | 0.257990171134824 | 12.49998697918023 | 0 | 5.541738410783121 | 2.301029995663981 | 4.833483331976126 | 2.301029995663981 | 2.301029995663981 | -6 | 9 | 36 | 4 | 7 | 42 | 7599060 | exp5 | 0.9999998559756664 | 42 | 0.7739705134044719 | 2 | 1 | 100 | 1.903089986991944,-1.301029995663981,2.301029995663981,-6,-0.3010299956639812,-3,2.301029995663981,1.903089986991944,0.6989700043360189,0.6989700043360189,-1.301029995663981,-6,2.301029995663981,1.477121254719662,1,1.477121254719662,1,-1.301029995663981,-0.3010299956639812,-3,-6,1.903089986991944,1.903089986991944,1,1.477121254719662,-0.3010299956639812,0.6989700043360189,-1.301029995663981,-3,2.301029995663981,1.477121254719662,0.6989700043360189,-0.3010299956639812,-6,1,-3 | 4.526747108334523,0.824888031466226,4.347823386445102,0.4561003316738806,0.7789416927493502,0.8941877572233543,0,5.673754841308623,1.057438090424463,1.601601548161443,0.7860261779905042,1.266348323306034,12.49998697918023,0.5233494153240975,0.6619009620889339,0.3966504893499123,0.6597819661565701,0.7658389239768177,0.8219881628053387,0.7946680134665979,1.341281635835031,5.050502499746212,3.030301882461408,0.9870918379995505,0.7423904698444517,0.9801095134012823,0.2988791955447274,0.6880733769604134,0.916522147225114,5.319143277507151,0.8810572334378359,0.7454444852168833,0.5113383612419217,1.119847483444187,0.5093378484274108,0.4670714510258886 | 0.256129166457669 | 0.5644406772111492 | 1129.309676044466 | 39317.04061124209 | 0.8720019016302841 | 22.67001140386491 | 0.3000030586436188 | 3.190253095690696 | 4.264093872089519 | 0.6791167117000405 | 7.176325755057048 | -0.03477378065375659 | 0.3936756503357535 | 0.04971757164252175 | -0.06866643163594202 | -0.0334255933863206 | 54.83941521805386 | 5.528448444550952 | -0.1247041887933517 | 47.98249665491507 | 4.7906449817634 | -0.123418231619115 | 48.10588765537344 | 1521.241791470397 | 5.939435678991746 | -0.1222694671455815 | 38.87908122770836 | 4.727067329887222 | 0.02880987281153338 | 1571.479760265 | 54739.70724496405 | 131.0854979041203 | 1 | 1.765526514465492 | 5.096288028509811 | 0 | 163.6015491080996 | 2.940288361762558 | 137.6944700157536 | 1 | 1.839829493486011 | 5.759267997099814 | 132.2181663378478 | 1 | 1.767692326868145 | 5.085763779463437 | 129.8610022030918 | 1 | 1.741178275348366 | 5.528448444550952 | 126.4266045032358 | 1 | 1.710836552043537 | 4.7906449817634 | 130.5159804184214 | 1 | 1.71478488931515 | 4.942677854612155 | 126.5673678429075 | 1 | 1.715449697243332 | 4.727067329887222 | 0.04875193061282054 | 0.04920885674061179 | 0.1568794096944919 | 58.57409370876723 | 0.1274395651660143 | 0.4008290595446733 | 6523.333085119923 | 100.1271711840828 | 226568.1367189886 | 63.9739161348579 | 54.83941521805386 | 47.98249665491507 | 1.626977167185993 | 46.10404508226414 | 38.87908122770836 | 78.09046476767209 | 135.6643254100138 | 1 | 1.839223539922158 | 5.761974562306676 | 137.7074580334908 | 1 | 1.839901202582666 | 5.762622726294994 | 0.1600595257250332 | 0.1651236332073655 | 0.1553647531392489 | 22.62317355663337 | 1.074649121508948 | 0.1550298307298998 | 11.02765496361144 | 0.5822266175525593 | 0.1551748064844922 | 110.9175537739921 | 1.303718500493837 | 0.004437974865094146 | 100 | 7620.57224036576 | 100.1820171124199 | 264301.4890716433 | 0.1650477137056485 | 0.1650896443467675 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2505.473461956673 | 3.190253095690696 | -0.1247041887933517 | 47.98249665491507 | 4.7906449817634 | 21.21481348706796 | 31.23504395850078 | 27.67407473473264 | 0.5407184013257643 | -59.2133022516179 | 4.7906449817634 | 26.58462846085418 | 33.6346972007241 | 47.98249665491507 | 21.83223375769735 | 34.85027881622872 | 1.710836552043537 | 25.06997712418609 | 8.463760056913385e-9 | 0.9999998559756664 | 6.18969960585545 | Noisy data | 10 |
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | er | ga | tp | ac5 | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | bmdu | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | a | acc | p | flag | mc6MthdId |
---|
aeid | m4id | spid | chid | casn | chnm | dtxsid | bmad | respMax | respMin | maxMean | maxMeanConc | maxMed | maxMedConc | logcMax | logcMin | nconc | npts | nrep | nmedGtbl | tmpi | m5id | modl | hitc | fitc | coff | actp | modelType | chidRep | stkc | stkcUnit | testedConcUnit | logc | resp | pow_a | pow_p | exp2_a | exp2_b | exp3_a | exp3_b | exp3_p | exp5_p | gnls_p | gnls_q | hill_p | pow_er | cnst_er | exp2_er | exp3_er | exp4_er | exp4_ga | exp4_tp | exp5_er | exp5_ga | exp5_tp | gnls_er | gnls_ga | gnls_la | gnls_tp | hill_er | hill_ga | hill_tp | poly1_a | poly2_a | poly2_b | pow_aic | pow_cov | pow_rme | pow_top | all_bmed | cnst_aic | cnst_rme | exp2_aic | exp2_cov | exp2_rme | exp2_top | exp3_aic | exp3_cov | exp3_rme | exp3_top | exp4_aic | exp4_cov | exp4_rme | exp4_top | exp5_aic | exp5_cov | exp5_rme | exp5_top | gnls_aic | gnls_cov | gnls_rme | gnls_top | hill_aic | hill_cov | hill_rme | hill_top | poly1_er | poly2_er | pow_a_sd | pow_ac50 | pow_p_sd | all_onesd | exp2_a_sd | exp2_ac50 | exp2_b_sd | exp3_a_sd | exp3_ac50 | exp3_b_sd | exp3_p_sd | exp4_ac50 | exp5_ac50 | exp5_p_sd | gnls_ac50 | gnls_p_sd | gnls_q_sd | hill_ac50 | hill_p_sd | poly1_aic | poly1_cov | poly1_rme | poly1_top | poly2_aic | poly2_cov | poly2_rme | poly2_top | pow_er_sd | exp2_er_sd | exp3_er_sd | exp4_er_sd | exp4_ga_sd | exp4_tp_sd | exp5_er_sd | exp5_ga_sd | exp5_tp_sd | gnls_er_sd | gnls_ga_sd | gnls_la_sd | gnls_tp_sd | hill_er_sd | hill_ga_sd | hill_tp_sd | poly1_a_sd | poly1_ac50 | poly2_a_sd | poly2_ac50 | poly2_b_sd | poly1_er_sd | poly2_er_sd | pow_success | cnst_success | exp2_success | exp3_success | exp4_success | exp5_success | gnls_success | hill_success | poly1_success | poly2_success | gnls_ac50_loss | er | ga | tp | ac5 | bmd | bmr | mll | top | ac10 | ac20 | ac50 | bmdl | bmdu | rmse | ac1sd | caikwt | hitcall | top_over_cutoff | a | acc | p | flag | mc6MthdId |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
704 | 1842410 | LEGTV002G10 | 32577 | 79538-32-2 | Tefluthrin | DTXSID5032577 | 3.763467929968328 | 22.88978034849851 | -26.55279825025137 | 22.88978034849851 | 0.7781512503836436 | 22.88978034849851 | 0.7781512503836436 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 4 | 9 | 5037056 | exp4 | 0.2411318116914611 | 15 | 22.58080757980996 | 2 | 1 | 20 | mM | uM | -1.698970004336019,-0.2218487496163564,0.7781512503836436,-1.154901959985743,1.301029995663981,-0.6989700043360187,1.698970004336019,0.3010299956639812 | -26.55279825025137,7.643488716816449,22.88978034849851,7.941246592240145,19.24904893698625,22.72625970498906,20.26645313099273,10.22016979195821 | 8.051875026642751 | 0.3000002363252646 | 2586.527394818691 | 5061.903524643174 | 16.99162030680426 | 61.30793025206805 | 0.3000001542012486 | 0.4110935896070254 | 0.5634256102787089 | 7.950665366879992 | 0.5634498524518311 | 2.176743421283692 | 2.869801913777267 | 2.623207281861648 | 2.319284740146711 | 2.105613497819531 | 1.018823124990093 | 20.26025144660328 | 1.982012717222342 | 0.4248866702697808 | 20.7377426492478 | 1.99625942425146 | 0.3960985797099487 | 4930.779736400695 | 21.81742856245767 | 1.996272080662291 | 0.3960554677803401 | 21.81711489655617 | 0.5150479432537712 | 2323.882444395881 | 4567.207855100587 | 68.5758988456374 | 1 | 12.72105378688701 | 26.03684923789126 | 0 | 72.9602916781216 | 18.54949195654765 | 73.57241312566146 | 1 | 15.49883885923806 | 25.67555887819936 | 71.90187282888056 | 1 | 13.22643934830849 | 26.53564273777775 | 67.91716461253762 | 1 | 12.29160032836853 | 20.26025144660328 | 68.74654825043743 | 1 | 12.20539126950889 | 20.7377426492478 | 72.70908001073246 | 0 | 12.08907864204856 | 21.62406269958069 | 68.70908001125854 | 1 | 12.08905260278873 | 21.81711489655617 | 2.623380636526907 | 2.623494262991935 | 18.2631789604329 | 4.960637316196675 | 0.697941144406865 | 6.885946392795786 | 32716.58150985923 | 25.06173541792207 | 63813.26545499676 | 9.809731117071673 | 1.018823124990093 | 0.4248866702697808 | 0.3479966996086568 | 0.3838306742682284 | 0.3960554677803401 | 0.635744845964724 | 71.56605507092407 | 1 | 15.49329425620499 | 25.75239716268856 | 73.57994628381844 | 1 | 15.50431136692914 | 25.7194709802226 | 1.15655148324573 | 0.3073701019975029 | 0.387701061369176 | 1.301060030418642 | 4.791141733238257 | 0.3929731812861924 | 0.8430161520344103 | 5.937095261163485 | 0.3920891185604444 | 1.260258162080632 | 10.91226236981797 | 0.2454616975843716 | 25 | 20164.12446138026 | 25.13535922520561 | 39136.75145557223 | 0.3073969378754904 | 0.3073430361679298 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4935.719934078368 | 2.105613497819531 | 1.018823124990093 | 20.26025144660328 | 0.07539350363763271 | 0.9015999983866408 | 9.289141683881516 | -30.95858230626881 | 20.26025144660328 | 0.154864266671847 | 0.3279877876552497 | 1.018823124990093 | 0.01524977302278195 | 3.811435874108677 | 12.29160032836853 | 0.6104667435797823 | 0.07436025429585817 | 0.2411318116914611 | 0.8972332532835738 | Multiple points above baseline, inactive,Borderline,Average number of replicates per conc is less than 2 | 8,11,13 | ||||||||||||||
704 | 1842408 | LEGTV002F02 | 34634 | 68157-60-8 | Forchlorfenuron | DTXSID1034634 | 3.763467929968328 | 30.30548040343731 | -15.78246312363302 | 30.30548040343731 | 1.698970004336019 | 30.30548040343731 | 1.698970004336019 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 2 | 7 | 5037054 | poly1 | 0.6460864720880574 | 15 | 22.58080757980996 | 2 | 1 | 20 | mM | uM | 0.7781512503836436,1.301029995663981,-0.6989700043360187,1.698970004336019,0.3010299956639812,-1.698970004336019,-0.2218487496163564,-1.154901959985743 | 17.31219744793772,5.892444361517972,-5.621637590571268,30.30548040343731,-12.04792113692197,-0.9033802904499949,3.950669112997684,-15.78246312363302 | 0.1234505358742655 | 1.403957219866202 | 11.70412663170948 | 39.21885087510036 | 6.797876599868359 | 27.22775499568563 | 0.8670700138038412 | 2.243572303903159 | 3.417276045729987 | 7.999999515229415 | 3.410031445934874 | 2.053160430913364 | 2.483165132916525 | 2.047714019672433 | 2.045418371135353 | 2.144069241774472 | 27.44498180992198 | 36.36657640836127 | 2.056168804647671 | 33.29374622826353 | 36.36657624507367 | 2.058394106808393 | 31.61205104146836 | 1534.112263771357 | 36.36657643578302 | 2.058279940276527 | 31.61029453570885 | 36.36657616615269 | 0.5785182000394039 | 12.45938588854816 | 44.18199252652262 | 65.0995287126822 | 1 | 9.38736161655436 | 29.97603473866884 | 0 | 67.9344363146865 | 14.5564438526066 | 65.01101796690389 | 1 | 9.336855219455533 | 30.17713885051414 | 67.00414392078824 | 1 | 9.328883445138253 | 30.18451270996992 | 65.8649681972613 | 1 | 9.540601853567534 | 36.36657640836127 | 67.2557220191338 | 1 | 9.530978553849964 | 36.36657624507367 | 71.33940383936331 | 1 | 9.604561582504878 | 36.36043012871301 | 67.33939320817458 | 1 | 9.604376235570829 | 36.36657616615269 | 2.085652025408799 | 2.049820013105159 | 0.5753788358968032 | 30.51789976345631 | 1.208640790059217 | 6.885946392795786 | 41.73861131597536 | 32.48057507982734 | 80.2181969794621 | 55.46148196934477 | 32.61409306497238 | 155.3113261559939 | 1.768535050305704 | 27.44498180992198 | 33.29374622826353 | 3.435165237165201 | 31.60892429289404 | 31.61029453570885 | 23.432436210259 | 63.26368385628203 | 1 | 9.335379666909818 | 28.92591000197019 | 65.04407548989566 | 1 | 9.347372572279864 | 30.0568815404299 | 0.3330141164367186 | 0.3322758677027563 | 0.3319875527085669 | 0.3157481584060974 | 34.05963965560971 | 26.97749639037905 | 0.334389570780719 | 37.91927313278114 | 50.50406303044664 | 0.3364006997413888 | 126.4453565783159 | 150.7398965927604 | 0.1378894246559652 | 25 | 81.28656120170228 | 31.22468556738295 | 189.8709620228806 | 0.3179896544722494 | 0.3317697682239624 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1534.17642118601 | 2.085652025408799 | 2.5 | 16.05678383713566 | 9.289141683881516 | -29.63184192814101 | 28.92591000197019 | 4.999999999999999 | 9.999999999999998 | 25 | 11.31118975184254 | 29.51384383733146 | 9.335379666909818 | 11.90273079105683 | 0.08823518845609243 | 0.6460864720880574 | 1.280995371832207 | 0.5785182000394039 | 39.03214726567279 | Multiple points above baseline, inactive,Average number of replicates per conc is less than 2 | 8,13 | ||||||||||
704 | 1842409 | LEGTV002F07 | 32392 | 66441-23-4 | Fenoxaprop-ethyl | DTXSID2032392 | 3.763467929968328 | 11.82202000041872 | -15.51937584178316 | 11.82202000041872 | -1.698970004336019 | 11.82202000041872 | -1.698970004336019 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 1 | 8 | 5037055 | poly1 | 0.00001432227153108321 | 13 | 22.58080757980996 | 2 | 1 | 20 | mM | uM | -1.698970004336019,0.3010299956639812,0.7781512503836436,-1.154901959985743,1.301029995663981,-0.6989700043360187,-0.2218487496163564,1.698970004336019 | 11.82202000041872,1.553696169494124,-15.51937584178316,-3.18010844609448,-2.140589126080783,8.784412793010326,-2.315749806346261,-0.3023091900039757 | 0.000001163243173042003 | 0.371275158646456 | 0.000001797829505777648 | 72.74913416945634 | 0.000005500575864409839 | 57.76084401258878 | 6.22085425509824 | 0.8997002598611641 | 6.745015045169553 | 7.999999994872401 | 7.540290076592129 | 1.80225413152565 | 1.801579678949913 | 1.80074945164374 | 1.802189441350072 | 1.80158870051793 | 7.782862626322558 | 3.226750921155688e-9 | 1.801591209473396 | 8.441755009402286 | 7.302557281932975e-10 | 1.563319486875444 | 0.002157113472191094 | 0.3339308415916757 | 7.623928704938419 | 1.801589018660463 | 157.944528963563 | 1.895515367843367 | 5.662423411973493e-10 | 0.0000223262545669987 | 56.36270470222716 | 61.5780037237116 | 1 | 7.748713087460874 | 0.000004971138582058439 | 0 | 57.57799866553477 | 7.748712496775653 | 61.5780047490661 | 1 | 7.748712562373631 | 0.000001776842803973729 | 63.57800185669078 | 1 | 7.748712510532352 | 0.000002767495920583712 | 61.57799866669821 | 1 | 7.748712497203208 | 3.226750921155688e-9 | 63.57799866627887 | 1 | 7.74871249686776 | 7.302557281932975e-10 | 64.94555137524486 | 1 | 6.978798723259373 | 7.623928557703294 | 63.57800538783228 | 1 | 7.748714090611704 | 1.895515367843367 | 1.801569355455974 | 1.801791564779594 | 7.72982644524005 | 6.885946392795786 | 29.2136078914714 | 45.42645739987168 | 7.782862626322558 | 8.441755009402286 | 0.00215711341620102 | 1886.618137891954 | 13.89759636931638 | 157.944528963563 | 59.57799867040296 | 1 | 7.748712498123487 | 2.831211705986746e-8 | 61.57800229689971 | 1 | 7.748713685123689 | 0.00003737589473088489 | 0.3905956734359877 | 1.343381900673757 | 0.3212711194493188 | 3.818735746599816 | 0.1026000354392676 | 25 | 30.58306067150831 | 0.347079299345627 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0.3339308431136041 | 1.801569355455974 | 2.5 | 16404887109.35875 | 9.289141683881516 | -27.78899933520148 | 2.831211705986746e-8 | 5 | 10 | 25 | 62.41443596324167 | 7.748712498123487 | 12160776211.53354 | 0.7310585791085764 | 0.00001432227153108321 | 1.253813308483351e-9 | 5.662423411973493e-10 | Bmd > ac50, indication of high baseline variability,Average number of replicates per conc is less than 2 | 9,13 | ||||||||||||||||||||||||||||||
704 | 1842411 | LEGTV002H08 | 34742 | NOCAS_34742 | Milbemectin (mixture of 70% Milbemcin A4, 30% Milbemycin A3) | DTXSID8034742 | 3.763467929968328 | 73.67532078350177 | -5.395088130329359 | 73.67532078350177 | 0.7781512503836436 | 73.67532078350177 | 0.7781512503836436 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 6 | 10 | 5037057 | exp4 | 0.9999994968056571 | 42 | 22.58080757980996 | 2 | 1 | 20 | mM | uM | 0.3010299956639812,-1.698970004336019,0.7781512503836436,-1.154901959985743,1.301029995663981,-0.2218487496163564,-0.6989700043360187,1.698970004336019 | 52.50565287274907,-5.395088130329359,73.67532078350177,5.395088130329359,72.53691394012041,19.22317269185714,30.26330127768545,69.87972321355599 | 28.14788638557633 | 0.3000000968964152 | 6119.261472113918 | 3551.239003137988 | 975.1669226858538 | 153230.6117998245 | 0.3000003501105035 | 1.094805881965073 | 1.364713018856813 | 0.5619058173970354 | 1.59050714992454 | 2.63553254897771 | 3.795906798840122 | 3.395498770118811 | 2.727845635618811 | 1.468967267927072 | 1.099878418012791 | 72.48760653689077 | 1.385097799783372 | 1.132980663465564 | 72.29651505256778 | 1.358123043399694 | 1.391585775765272 | 524.1224234965719 | 88.41038117121148 | 1.597002118919094 | 1.077282613722834 | 73.26305717696057 | 1.739750463141079 | 8413.5045447357 | 4888.583862175059 | 73.54169876654271 | 1 | 15.2861480042891 | 91.02002602025269 | 0 | 88.28390953083002 | 49.58992816204983 | 86.10951984809975 | 1 | 34.32894405417382 | 86.76609362549449 | 75.92329672154494 | 1 | 15.63016093572911 | 91.8010727392276 | 59.2793317878772 | 1 | 8.238704361671774 | 72.48760653689077 | 61.10190561453248 | 1 | 8.62848952975195 | 72.29651505256778 | 65.36002423995862 | 1 | 9.055176915896654 | 75.01351487350438 | 63.48641699639106 | 1 | 9.621896825468774 | 73.26305717696057 | 3.393356939188565 | 3.395444102465724 | 8.463344228881985 | 4.960631989323517 | 0.09202961052734752 | 6.885946392795786 | 44830.33042686954 | 25.08799672975325 | 25840.49536754701 | 1604.028096378901 | 5.342280307284645 | 660507.3822297514 | 0.1054190137078926 | 1.099878418012791 | 1.132980663465564 | 0.2147453097848282 | 1.158904104169734 | 0.3461607578247413 | 0.7944942746221946 | 1.077282613722834 | 0.4118849346917922 | 84.09047084550053 | 1 | 34.28245596585091 | 86.98752315705393 | 86.11783010298875 | 1 | 34.3417360780736 | 86.93271261079072 | 0.3277273956504853 | 0.3154107490786174 | 0.3499555166316232 | 0.3801021109960385 | 0.1580467176701573 | 2.557860936885942 | 0.4212709024359285 | 0.1485229561872174 | 2.346998337980212 | 0.4418044445090503 | 0.4322859035235454 | 1067.600545578146 | 26.85233220398398 | 0.3965733263953214 | 0.1694908330477647 | 3.405356028588671 | 0.5875701839815818 | 25 | 52103.4262311332 | 25.12655125481741 | 29886.90609902708 | 0.3150763970850645 | 0.3153392335770476 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 902.1729967630253 | 1.468967267927072 | 1.099878418012791 | 72.48760653689077 | 0.08139164245040806 | 0.2176052685800904 | 9.289141683881516 | -26.6396658939386 | 72.48760653689077 | 0.167184921951392 | 0.3540817637185837 | 1.099878418012791 | 0.1727659467693829 | 0.2697433120933787 | 8.238704361671774 | 0.1583847235750666 | 5.031943424985008e-7 | 0.9999994968056573 | 3.210142342371477 | 0.59228230830365 | Average number of replicates per conc is less than 2 | 13 | |||
704 | 1842412 | LEGTV003B07 | 23892 | 71751-41-2 | Abamectin | DTXSID8023892 | 3.763467929968328 | 77.95705815614956 | -28.22028225978724 | 77.95705815614956 | 1.698970004336019 | 77.95705815614956 | 1.698970004336019 | 1.698970004336019 | -1.698970004336019 | 8 | 8 | 1 | 5 | 11 | 5037058 | hill | 0.9999986614193673 | 41 | 22.58080757980996 | 2 | 1 | 20 | mM | uM | -0.2218487496163564,-1.698970004336019,0.7781512503836436,-1.154901959985743,1.301029995663981,-0.6989700043360187,0.3010299956639812,1.698970004336019 | 64.23854892075744,-28.22028225978724,71.52551303778179,-8.36715608785845,77.90911291815605,1.215720341597959,77.60553886175157,77.95705815614956 | 30.82228813134802 | 0.3000004325120875 | 9745.30422459993 | 4985.409545697486 | 743.0734773552446 | 48000.25079936882 | 0.3003650005778165 | 4.387719474863923 | 5.312129658102232 | 6.044467438794108 | 5.312112708921902 | 3.250040735544445 | 4.016143460737711 | 3.676700377308991 | 3.320916603363695 | 2.55983470322537 | 0.4227743529273414 | 77.51175315148927 | 1.566158921380688 | 0.4808129543908409 | 76.49260417613746 | 1.566171012426722 | 0.4392198763519543 | 3693.146065235527 | 76.49829109592685 | 1.56618318750266 | 0.4392211414112244 | 76.4982866415209 | 1.964864684075168 | 13315.49664400403 | 6833.361453964935 | 83.17121500215309 | 1 | 27.53800756189408 | 99.66819933343275 | 0 | 91.47566405075946 | 59.45598607857977 | 90.43010743722112 | 1 | 44.39325952551422 | 98.2300154558304 | 85.41740122713443 | 1 | 27.91524176610176 | 100.7298807877703 | 73.1330171088266 | 1 | 15.55408881626592 | 77.51175315148927 | 64.42879073216514 | 1 | 10.58687765959307 | 76.49260417613746 | 68.42786525704236 | 1 | 10.58654081202113 | 76.49829109470431 | 64.42786525848331 | 1 | 10.58654076385496 | 76.4982866415209 | 3.675479917703469 | 3.675300474185758 | 14.10969315543279 | 4.960644811507054 | 0.1304028975350829 | 6.885946392795786 | 95296.73353627026 | 25.06268265173192 | 48443.77844798849 | 1550.68117533334 | 5.520304040411192 | 261983.9706240629 | 0.1466564478154249 | 0.4227743529273414 | 0.4808129543908409 | 3.367839554935385 | 0.4392198767408624 | 3.395825521805466 | 151123.9464489836 | 0.4392211414112244 | 3.395606105385336 | 88.41948218774404 | 1 | 44.36648863230358 | 98.2432342037584 | 90.43488820771466 | 1 | 44.40668518959494 | 98.14296226438184 | 0.303588605041555 | 0.3103300882267534 | 0.3148286478417944 | 0.3265560847968896 | 0.1873471178291782 | 6.138860820650144 | 0.4233459639266265 | 0.08381003754668022 | 2.37147868048167 | 0.4232676288363896 | 0.09134632329842142 | 397472143.9662275 | 2.374785908301951 | 0.4232684668587263 | 0.09134005178183088 | 2.374805818081386 | 0.744525928526376 | 25 | 108969.207083015 | 25.0907974628384 | 55447.95612242906 | 0.3102154232611201 | 0.3101964438666455 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3693.146065255056 | 1.56618318750266 | 0.4392211414112244 | 76.4982866415209 | 0.2523243288762269 | 0.3026161445689406 | 9.289141683881516 | -28.21393262924166 | 76.4982866415209 | 0.2904343777444861 | 0.3383343045279963 | 0.4392211414112244 | 0.2465292822610198 | 0.34140137679409 | 10.58654076385496 | 0.2841483864185201 | 0.000001338580632686677 | 0.9999986614193672 | 3.387756898026971 | 0.3728438377252359 | 5.312112708921902 | Average number of replicates per conc is less than 2 | 13 | ||
704 | 1842413 | Strychnine nitrate | 3.763467929968328 | 101.9030265167291 | -13.65625239886388 | 90.10574793432083 | 0 | 92.78949471220062 | 1 | 1 | -2 | 5 | 120 | 28 | 4 | 12 | 5037059 | hill | 0.9999999999995097 | 41 | 22.58080757980996 | 2 | 0,-1,-1.301029995663981,-1.301029995663981,0,-2,-1,1,1,-2,-2,0,0,0,-2,-2,-2,0,0,-2,-1.301029995663981,0,0,-1,-1.301029995663981,1,-2,-1.301029995663981,-2,1,-1.301029995663981,0,-1,-1.301029995663981,0,-1,-1.301029995663981,1,-2,-1.301029995663981,0,-2,-1.301029995663981,-1,0,-2,-1.301029995663981,0,-2,-1.301029995663981,-1.301029995663981,1,-2,0,0,-2,-1.301029995663981,0,-1.301029995663981,-1,-1.301029995663981,-2,-1.301029995663981,1,-2,0,0,-2,-1.301029995663981,0,0,-1,-2,0,0,0,0,-2,-2,0,0,-1,-1.301029995663981,0,-2,-1.301029995663981,1,0,-1.301029995663981,0,-1,0,0,-1,-1.301029995663981,1,-2,-1.301029995663981,-1.301029995663981,1,-2,0,1,0,0,1,-2,0,0,-2,-2,0,-1.301029995663981,0,0,-2,-1,-1.301029995663981,-1.301029995663981,-1.301029995663981 | 87.54658046017934,78.13232047400955,70.93317595233076,57.12698428271491,99.1261742792355,37.51266678271632,67.39566754400876,87.16917249987551,97.84412575893514,36.18215385187194,18.6767597801383,86.14639524902825,92.14700970993877,88.8633754305396,52.58858221584433,15.5821338190493,6.74371123267608,90.99910854039037,93.537388378317,4.532945470243127,98.29029571012077,87.5125820151942,95.77948529616398,76.69719021917145,79.44282282360146,93.41848845767122,43.82855649076092,60.07863548064282,48.55573840229915,93.38936767278678,68.38088898210545,94.44174081967034,70.23063280229242,67.58951070420052,88.25476716259126,78.28663544945115,73.35709503155529,87.41418530525512,34.29624566401982,51.68953065049507,94.77671619175891,9.717713327456835,68.42696208430887,89.1457018171264,98.63621639131843,21.81986732528967,73.31442418286787,84.44684859725044,101.9030265167291,52.3796866174266,76.70392442439466,95.96954413243368,37.93266445213204,85.53995501238715,93.19761923373274,9.374938681003872,97.00772826137256,94.52068000480857,70.03934960306947,70.2207854474335,80.60056702989422,49.65332555177622,50.62118183723142,-13.65625239886388,25.10392941942042,84.06775274470809,93.89545097387872,13.05234184109041,68.04669508697455,88.31017585712213,95.74909219574056,71.26573270110495,29.65748317930647,89.44967487095494,87.91122190917191,89.16083809801721,94.23105830572473,11.03171547348445,35.95756511831335,83.96484285494779,91.13344836386635,74.37468254708669,75.90341444167755,84.57925357612386,98.09697348327087,80.87025230976089,95.69038769184029,88.16849658860856,80.80349695840118,81.03526087553716,70.7375590556676,89.62211351249503,92.83767649850626,69.7285258942436,77.48304372596083,85.86002702419643,32.2784448599929,46.17015103402697,80.62410063741106,95.95106666573619,10.20724914281911,79.02545835944098,87.98083471817364,91.89339887484604,95.37517669787248,92.18962175161448,25.41315377084938,85.26467195488401,94.339523858436,21.43204097853926,30.4589935716333,93.86466610169768,70.85250358307763,84.70694885833929,90.17107266940845,42.17348917186203,67.85218078295692,80.66923781410267,52.40470406123019,66.29938729985028 | 87.09928260115939 | 0.3000000184693846 | 31883.44719955698 | 2940.875688083027 | 91.76407834702847 | 10.74787786809403 | 5.705870147581669 | 0.7347141145071212 | 1.14249184755643 | 7.166661748586264 | 1.142517370986631 | 3.260955964705928 | 4.280418232198627 | 4.136618684570908 | 4.195352905645352 | 2.22008241758199 | 0.022051638521133 | 89.00270902788958 | 2.177704389198515 | 0.02017472381818019 | 90.09083963206248 | 2.141472844459042 | 0.01923935560120662 | 152.6017396979347 | 90.96174103754969 | 2.141463902181826 | 0.01923940851801358 | 90.96158402591846 | 10.85728555486508 | 43956.72490990105 | 4063.958522468021 | 1201.405136589056 | 1 | 38.55227695861075 | 173.785923625569 | 0 | 1403.090413337808 | 74.8904479807055 | 1374.431165628205 | 1 | 65.81746775643614 | 108.5993407555391 | 1391.16250302868 | 1 | 70.11489384972245 | 86.24941190716868 | 958.5585213667588 | 1 | 17.13685942535133 | 89.00270902788958 | 951.462915769895 | 1 | 16.56367004417133 | 90.09083963206248 | 949.1076392567716 | 1 | 16.52317459801129 | 90.94223261829664 | 945.1076391339816 | 1 | 16.52318715556179 | 90.96158402591846 | 4.136728636883216 | 4.136765485844394 | 0.9921257986045094 | 6.885946392795786 | 199788.2012717345 | 5.004250432627864 | 18377.63969018875 | 9.093200201104786 | 0.022051638521133 | 0.02017472381818019 | 0.0740314724723753 | 0.01923213377527789 | 0.1132871603570413 | 5416.430149594935 | 0.01923940851801358 | 0.113289059523448 | 1372.405512117827 | 1 | 65.81045931392097 | 108.5728555486508 | 1374.442586810751 | 1 | 65.82134141098302 | 108.4284866657759 | 0.07550543011989125 | 0.08755079994277236 | 0.001758130783875126 | 1.26487457041259 | 0.08793429019100046 | 0.001896252806984504 | 1.229548672184863 | 0.08841293445887041 | 0.00163880706134835 | 314310.1153126622 | 1.359207718507748 | 0.08841259880190765 | 0.001638789350228368 | 1.35918679158558 | 1.724413789883238 | 5 | 229686.482934115 | 5.006136528441479 | 21186.12166910065 | 0.07551023114530929 | 0.07551301062757607 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 152.6093800236882 | 2.141463902181826 | 0.01923940851801358 | 90.96158402591846 | 0.001462007378119528 | 0.002869845955059214 | 9.289141683881516 | -468.5538195669907 | 90.96158402591846 | 0.002811779188233831 | 0.005717847375539592 | 0.01923940851801358 | 0.002556132850019782 | 0.003219636919114361 | 16.52318715556179 | 0.002152983606346318 | 3.550619862824629e-100 | 0.9999999999995096 | 4.028269746527992 | 0.007294932270379909 | 1.142517370986631 |
Similar to the other _batch
functions,
get_bioactivity_details_batch()
retrieves data for a list
(or vector) of assay endpoint ids (aeid), sample ids (spid), Level 4 IDs
(m4id), or chemical DTXSIDs.
Conclusion
In this vignette, a variety of functions that access different types
of data found in the Bioactivity
endpoints of the CTX APIs
were listed. We encourage the reader to explore the data accessible
through these endpoints work with it to get a better understanding of
what data is available. Additionally, experienced ToxCast/invitrodb
users may find it easier to continue to use tcpl, which has
integrated ccdR’s bioactivity functions to make the API data retrievable
in a familiar format.