ctlr: Clinical Tolerance Limits for Assessing Agreement

Implements clinical tolerance limits (CTL) methodology for assessing agreement between two measurement methods. Estimates the true latent trait using Best Linear Unbiased Predictors (BLUP), models bias and variance components, and calculates overall and conditional agreement probabilities. Provides visualization tools including tolerance limit plots and conditional probability of agreement plots with confidence bands. This package is based on methods described in Taffé (2016) <doi:10.1177/0962280216666667>, Taffé (2019) <doi:10.1177/0962280219844535>, and 'Stata' package Taffé (2025) <doi:10.1177/1536867X251365501>.

Version: 0.1.0
Depends: R (≥ 4.1.0)
Imports: binom (≥ 1.1-1.1), dplyr (≥ 1.1.0), ggplot2 (≥ 3.3.0), lme4 (≥ 1.1-35), lmtest (≥ 0.9-40), MASS (≥ 7.3-60), mfp2 (≥ 1.0.1), sandwich (≥ 3.0-0), stats, utils
Suggests: testthat (≥ 3.0.0), withr (≥ 2.0.0)
Published: 2026-03-20
DOI: 10.32614/CRAN.package.ctlr (may not be active yet)
Author: Eliane Maalouf ORCID iD [aut], Patrick Taffé ORCID iD [cre, aut, cph]
Maintainer: Patrick Taffé <patrick.taffe at unisante.ch>
License: GPL (≥ 3)
NeedsCompilation: no
Materials: README, NEWS
CRAN checks: ctlr results

Documentation:

Reference manual: ctlr.html , ctlr.pdf

Downloads:

Package source: ctlr_0.1.0.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

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