Package: MiRKAT
Version: 1.0
Date: 2017-07-25
Title: Microbiome Regression-Based Kernel Association Test
Authors@R: c(person("Haotian", "Zheng", role = c("aut"),
                    email = "ht-zh14@mails.tsighua.edu.cn"),
             person("Xiang", "Zhan", role = "aut"),
             person("Anna", "Plantinga", role = "aut"),
             person("Michael", "Wu", role = "aut"),
             person("Ni", "Zhao", role = c("aut", "cre"), email = "nzhao10@jhu.edu"))
Author: Haotian Zheng [aut], Xiang Zhan [aut], Anna Plantinga [aut], Michael Wu [aut], Ni Zhao [aut, cre]
Maintainer: Ni Zhao <nzhao10@jhu.edu>
Depends: R (>= 2.13.0), survival, PearsonDS, GUniFrac, MASS
Description: Test for overall association between microbiome composition data with a continuous or dichotomous outcome via phylogenetic kernels. The phenotype can be univariate continuous or binary phenotypes (Zhao et al. (2015) <doi:10.1016/j.ajhg.2015.04.003>), survival outcomes (Plantinga et al. (2017) <doi:10.1186/s40168-017-0239-9>), multivariate (Zhan et al. (2017) <doi:10.1002/gepi.22030>) and structured phenotypes (Zhan et al. (2017) <doi:10.1111/biom.12684>). For all these effect, the microbiome community effect was modeled nonparametrically through a kernel function, which can incorporate the phylogenetic tree information.
License: GPL (>= 2)
NeedsCompilation: yes
Packaged: 2017-07-25 20:54:07 UTC; dell
Repository: CRAN
Date/Publication: 2017-07-25 21:52:56 UTC
