ssMRCT: Regional Consistency Evaluation and Sample Size Calculation for MRCTs

Calculate conditional regional consistency probabilities and sample sizes for multi-regional clinical trials under fixed-effects and random-effects models. Supports two independent trials, regional fraction selection under symmetric designs, and doubly robust regional treatment-effect estimation. Methods include Qing et al. (2025) <doi:10.1002/sim.70306> and Ren and Xu (2026) <doi:10.1002/pst.70090>.

Version:	0.2.0
Depends:	R (≥ 3.5.0)
Imports:	stats, mvtnorm, utils
Suggests:	testthat (≥ 3.0.0)
Published:	2026-11-12
DOI:	10.32614/CRAN.package.ssMRCT (may not be active yet)
Author:	Kunhai Qing [aut, cre], Xinru Ren [aut], Jin Xu [aut]
Maintainer:	Kunhai Qing <kunhaiq at stu.ecnu.edu.cn>
License:	MIT + file LICENSE
NeedsCompilation:	no
Materials:	README, NEWS
CRAN checks:	ssMRCT results

Documentation:

Reference manual:

ssMRCT.html , ssMRCT.pdf

Downloads:

Package source:	ssMRCT_0.2.0.tar.gz
Windows binaries:	r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries:	r-release (arm64): not available, r-oldrel (arm64): not available, r-release (x86_64): not available, r-oldrel (x86_64): not available

Linking:

Please use the canonical form https://CRAN.R-project.org/package=ssMRCT to link to this page.